Glucagon signalling in the dorsal vagal complex is sufficient and necessary for high-protein feeding to regulate glucose homeostasis in vivo.

Glucagon Action in the Dorsal Vagal Complex and the Regulation of Glucose Homeostasis during High-protein Feeding

Designing a glycemic control strategy to maintain glucose homeostasis and prevent hypoglycemia for subjects with type 1 diabetes

This paper presents using the fractional PImDn controller module which manipulates insulin infusion rate to maintain normoglycemia in subjects with type 1 diabetes. To prevent severe hypoglycemia, a conventional proportional controller is used to regulate glucagon infusion rate when the blood glucose levels fall below a threshold. Two sets of controller parameters are obtained and evaluated. Fo...

Glucagon-like peptide 1 interacts with ghrelin and leptin to regulate glucose metabolism and food intake through vagal afferent neuron signaling.

Emerging evidence has suggested a possible physiologic role for peripheral glucagon-like peptide 1 (GLP-1) in regulating glucose metabolism and food intake. The likely site of action of GLP-1 is on vagal afferent neurons (VANs). The vagal afferent pathway is the major neural pathway by which information about ingested nutrients reaches the central nervous system and influences feeding behavior....

The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose

Title: The CNS glucagon-like peptide-2 receptor in the control of energy balance and 1 glucose homeostasis 2 3 Xinfu Guan 4 USDA/ARS Children's Nutrition Research Center, Department of Pediatrics; Division 5 of Diabetes, Endocrinology & Metabolism, Department of Medicine, Baylor College of 6 Medicine, Houston, TX, USA 7 8 Running head: the CNS GLP-2 promotes glycemic control 9 Address for repri...

The Effect of Maternal High-Fat Feeding on Energy Homeostasis in Stressed Adult Male Rat Offspring

Introduction: In the present study the effect of chronic maternal high-fat diet consumption on energy homeostasis and glucose metabolism in response to chronic stress was investigated in adult male rats. Materials and Methods: Female rats were divided into two groups of normal and high fat diets. Each group received their diet from 3 weeks before pregnancy until the end of lactation. At 8 weeks...